This site provides INTERCEPT product information for Health Care Professionals in the United States.

Cerus Websites

Resources

Outpatient Coding and Billing Information Guide

Download View

Methodologies for Reducing the Risk of TA-GVHD from Platelet Transfusions

Download View

Best Practices Platelet Handling Guide (Hospitals)

Download View

Platelet Economic Model Poster

Download View

Implementation Guide for Pathogen Reduced Platelets

Download View

Septic Transfusion Reaction Awareness Poster

Download View

CMV Mitigation Sheet

Download View

Sample Labels Sheet

Download View

Sample SBAR Sheet

Download View

Sample Tie Tags Sheet

Download View

Nurse Training Module

Download View

Post Training Test

Download View

ISBT Platelet Codes

Download View

Nurse Handout Template

Download View

INTERCEPT Blood System for Platelets and Plasma

WARNINGS AND CONTRAINDICATIONS

CONTRAINDICATIONS
Contraindicated for preparation of platelet or plasma components intended for patients with a history of hypersensitivity reaction to amotosalen or other psoralens.

Contraindicated for preparation of platelet or plasma components intended for neonatal patients treated with phototherapy devices that emit a peak energy wavelength less than 425 nm, or have a lower bound of the emission bandwidth <375 nm, due to the potential for erythema resulting from interaction between ultraviolet light and amotosalen.

WARNINGS AND PRECAUTIONS
Only INTERCEPT Processing Sets for platelets or plasma are approved for use with the INTERCEPT Blood System. Use only the INTERCEPT INT100 Illuminator for UVA illumination of amotosalen-treated platelet or plasma components. No other source of UVA light may be used. Please refer to the Operator’s Manual for the INT100 Illuminator. Discard any platelet or plasma components not exposed to the complete INT100 illumination process.

Tubing components and container ports of the INTERCEPT Blood System contain polyvinyl chloride (PVC). Di(2-ethylhexyl)phthalate (DEHP) is known to be released from PVC medical devices, and increased leaching can occur with extended storage or increased surface area contact. Blood components will be in contact with PVC for a brief period of time (approx. 15 minutes) during processing. The risks associated with DEHP released into the blood components must be weighed against the benefits of therapeutic transfusion.

PLASMA
Amotosalen-treated plasma may cause the following adverse reaction: Cardiac Events

In a randomized controlled trial of therapeutic plasma exchange (TPE) for TTP, five patients treated with INTERCEPT Blood System processed plasma and none with conventional plasma had adverse events in the cardiac system organ class (SOC) reported. These events included angina pectoris (n=3), cardiac arrest (n=1), bradycardia (n=1), tachycardia (n=1) and sinus arrhythmia (n=1). None of these events resulted in documented myocardial infarction or death. Monitor patients for signs and symptoms of cardiac events during TPE for TTP.