This site provides INTERCEPT product information for Health Care Professionals in the United States.

The INTERCEPT® Blood System
for Platelets and Plasma,
Pathogen Reduction System

US Health Care Professionals

Safe Blood is Critical to Improving Patient Outcomes

But the continued risk of transfusion-transmitted infections (TTI) from bacteria and emerging pathogens, as well as blood shortages, have brought global attention to the importance of blood safety and availability.1-10

Final Guidance

On December 2020 the FDA issued the Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to…


The INTERCEPT® Blood System has significantly enhanced blood safety at >200 blood centers in >30 countries worldwide.

Blood System

The INTERCEPT® Blood System offers proven pathogen reduction for a broad range of viruses,…


Effective in reducing the risk of transfusion-transmitted infections (TTI),11 pathogen reduction for platelet components provides a solution to blood centers and hospital clients that ultimately benefits patients who need it most.

Not only does pathogen reduction comply with the FDA’s guidance on addressing bacterial contamination,1 it reduces risk beyond bacteria with mitigation of TTI due to viruses and parasites, as well as TA-GVHD due to T-Cells.11

Blood Matters

Certain non-enveloped viruses (e.g., HAV, HEV, B19, and poliovirus) and Bacillus cereus spores have demonstrated resistance to the INTERCEPT process. There is no pathogen inactivation process that has been shown to eliminate all pathogens.

1. Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion: Guidance for Industry, December 2020.  2.Kleinman S et al. Transfusion 2013;53:1603-1618.  3. Stramer SL, Hollinger FB, et al. Transfusion 2009;49(Suppl 2):1S-29S.  4. Rasongles P, et al. Transfusion 2009;49:1083-91.  5. Succo T et al. Euro Surveill. 2016 May 26;21(21).  6. Gjenero-Margan I et al. Euro Surveill. 2010 Sep 2;15(35).  7. Danis K et al. Euro Surveill. 2011 Aug 25;16(34).  8. Barzon L et al. Euro Surveill. 2009 Aug 6;14(31).  9. Schmidt M et al. Transfus Med Hemother 2014;41:10-17.   10. ABC News; “The Nation Has a Major Blood Shortage,” September 19, 2018. 11. The INTERCEPT Blood System for Platelets Package Insert, Cerus Corporation.